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KMID : 0980720060250020187
Keimyung Medical Journal
2006 Volume.25 No. 2 p.187 ~ p.191
Treatment of Cerebrospinal Fluid Leak using a Fibrin Glue in Patient with Spontaneous Intracranial Hypotension: Technical Note
Kim Eal-Maan

Abstract
Spontaneous intracranial hypotension due to a spinal cerebrospinal fluid (CSF) leak is rare but important cause of postural headache. For most patients with intracranial hypotension, spinal epidural blood patching is an effective treatment. The author describe a 38-year-old female patient of lumbar CSF fistula treated with percutaneous placement of fibrin glue. This patient showed typical magnetic resonance imaging findings including diffuse dural enhancement and subdural fluid collections. The fistula site was clearly detected on the myelography computerized tomography. The patient got symptom-free initially with lumbar blood patch, but she was rehospitalized for recurrent headache and dizzy feeling. The patient became asymptomatic within days of the novel procedure with injecting of fibrin glue into the dural CSF leaking point. Transcutaneous patching of spinal CSF fistula with a biological glue is a safe, effective, and less invasive treatment for spontaneous intracracranial hypotension in patients in whom conservative and traditional methods has failed.
KEYWORD
Autologous epidural blood patch, Cerebrospinal fluid leak, Fibrin glue, Intracranial hypotension, Orthostatic headache
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